Our Firm
Healthcare & Life Sciences - Sixth Street

Healthcare &
Life Sciences


Our dedicated team of seasoned healthcare investors provides strategic capital tailored to healthcare and pharma business timelines, whether to develop or launch new medicines, make asset acquisitions, or provide growth capital to finance strategic initiatives.

We are passionate about forming long-term partnerships with companies creating new technologies to address our most pressing healthcare challenges and improve patient care. Our experienced life sciences and technology teams focus on collaborating to develop AI and software-related themes within the healthcare space.

We invest across the sector and have partnered with companies in drug development and marketing, devices and diagnostics, generics, pharma and healthcare business services, and contract research, development and manufacturing.

Healthcare IT and Software

Healthcare Data and AI

OTC, Consumer, Cosmeceuticals

Pharma Services, CROs, CDMOs, Life Science Tools

Medical Devices


Pharmaceuticals & Biotechnology


Transaction Types

We provide flexible and custom solutions and typically make investments in the form of non-dilutive financing or growth capital. We can help fund launches, capital projects, R&D, product acquisitions, business carveouts and other strategic initiatives. Our partnerships usually include the following types, although these elements are often combined or take the form of novel structures.

Working with both private and public companies, we can offer custom financings which sit between common equity and secured debt. Our solutions often include convertible preferred equity, redeemable preferred equity or convertible debt with the ability to combine these with a secured financing.
2018 Case study: Caris Life Sciences

2020 Case study: Caris Life Sciences

2021 Case study: Caris Life Sciences

We seek to work with companies about to commence commercial operations through to profitability with secured debt or debt-like financing. We can tailor terms and structure to reflect a company’s stage of growth.
Case study: Biohaven

Case study: Nektar Therapeutics

Our team can work with companies on either passive royalty financings (company receives a passive third-party royalty) or synthetic royalty financings (company creates royalty on its own product). Royalty financings can include traditional royalty sales, structured royalty purchases (including annual or cumulative caps) or royalty-backed debt.

Case study: Immunogen

We can work directly with companies to help bring new products or therapies to the market. Our structures can help companies achieve their financial, accounting and strategic aims all while retaining control of the development of their assets.

Case study: Clovis Oncology

We have worked directly with healthcare funds to help fund the exit of assets at the end of fund life, acquire earnouts, or help fund incremental investments post LP commitment period. We can transact at the fund or asset level.

Select Investments

Alliance HealthCare Services

Irvine, California | www.alliancemedical.com

Alliance HealthCare Services is a leading national provider of outsourced medical services including radiology, oncology and interventional.


New Haven, Connecticut | www.biohavenpharma.com

Biohaven is a biopharmaceutical company focused on the development and commercialization of best-in-class therapies to improve the lives of patients with neurological and neuropsychiatric diseases.


Caris Life Sciences

Irving, Texas | www.carislifesciences.com

Caris Life Sciences is a leading innovator in molecular science focused on fulfilling the promise of precision medicine.


Clovis Oncology

Boulder, Colorado | www.clovisoncology.com

Clovis Oncology, Inc. is a biopharmaceutical company focused on acquiring, developing and commercializing innovative anti-cancer agents in the U.S., Europe and additional international markets.



San Francisco, CA | www.datavant.com/

Datavant’s mission is to connect the world’s health data to improve patient outcomes.


ROCKVILLE, MD, USA | https://drfirst.com/

DrFirst provides healthcare technology solutions and consulting services that securely connect people at touchpoints of care to improve patient outcomes.


Waltham, Massachusetts | www.immunogen.com

Immunogen is developing the next generation of antibody-drug conjugates (ADCs) aimed at disrupting the progression of cancer and improving outcomes for patients.



Cambridge, Massachusetts | www.ironwoodpharma.com

Ironwood Pharmaceuticals is a GI-focused healthcare company focused on creating medicines that make a difference for patients living with GI diseases.



Miramar, Flordia | https://www.mdlive.com/

MDLIVE is one of the largest and fastest growing virtual care delivery platforms.



Richardson, Texas | www.medeanalytics.com

MedeAnalytics is a healthcare analytics innovator enabling healthcare providers and payers across the U.S. and U.K. to make smarter decisions in today’s new healthcare economy.


Carlsbad, California | www.medsphere.com

Medsphere Systems Corporation is an organization of committed clinical and technology professionals working to positively impact patient care by delivering award-winning healthcare IT solutions for providers of every size and budget.



San Francisco, California | www.nektar.com

Nektar Therapeutics is a research-based, development stage biopharmaceutical company whose mission is to discover and develop innovative medicines to address the unmet medical needs of patients, including treatments of cancer, autoimmune disease and chronic pain.



Boca Raton, Florida | www.therapeuticsmd.com

TherapeuticsMD, Inc. is an innovative, leading healthcare company focused on developing and commercializing novel products exclusively for women.



Santa Rosa, CA | www.visiquate.com

VisiQuate is a leading provider of advanced analytics and AI-powered automation offerings to healthcare providers