Healthcare and
Life Sciences

Healthcare Sixth Street Healthcare Sixth Street

Our Approach

Strategic Capital and Tailored Solutions

Our team of seasoned healthcare investors provides strategic and often non-dilutive capital tailored to healthcare and pharma business timelines, whether to develop or launch new medicines, acquire assets, or provide growth capital to finance strategic initiatives.

Long-Term Partnerships

We are passionate about forming long-term partnerships with companies creating new technologies to address our most pressing healthcare challenges and improve patient care. Our experienced life sciences and technology teams focus on collaborating to develop AI and software-related themes within the healthcare space.

Broad Sector Expertise

We invest across the sector and have partnered with companies in drug development and marketing, devices and diagnostics, generics, pharma and healthcare business services, and contract research, development and manufacturing.

Healthcare IT Sixth Street

Healthcare IT and Software

Healthcare Data Sixth Street

Healthcare Data and AI

OTC Consumer Sixth Street

OTC, Consumer, Cosmeceuticals

Pharma Services Care Sixth Street

Pharma Services, CROs, CDMOs, Life Science Tools

Medical Devices Sixth Street

Medical Devices

Diagnostics Sixth Street


Pharmaceuticals and Biotechnology Sixth Street

Pharmaceuticals and Biotechnology

Consumer Services Sixth Street

Consumer Services


Janice Chen of Mammoth Biosciences speaks with David Stiepleman on Sixth Street’s It’s Not Magic podcast

Healthcare & Life Sciences Sixth Street


Our Solutions

Working with both private and public companies, our custom financing solutions include and often combine common equity, convertible preferred equity, redeemable preferred equity, or convertible debt.

Case Study: Caris Life Sciences

We seek to work with companies about to commence commercial operations through to profitability with secured debt or debt-like financing. We can tailor terms and structure to reflect a company’s stage of growth.

Case Study: Biohaven

Our team can work with companies on either passive royalty financings (company receives a passive third-party and typically non-dilutive royalty) or synthetic royalty financings (company creates royalty on its own product). Royalty financings can include traditional royalty purchases, structured royalty acquisitions (including annual or cumulative caps), or royalty-backed debt.

Case Study: Immunogen

We can work directly with companies to help bring new products or therapies to the market. Our structures can help companies achieve their financial, accounting, and strategic aims all while retaining control of the development of their assets.

Case Study: Clovis Oncology

We have worked directly with healthcare funds to help fund the exit of assets at the end of fund life, acquire earnouts, or help fund incremental investments post-LP commitment period. We can transact at the fund or asset level.

Reproduced with permission from Bloomberg L.P.

Chief Science Advisor

We welcomed Jennifer Doudna, Ph.D., Nobel laureate and co-discoverer of CRISPR, as our Chief Science Advisor in February 2022 . Dr. Doudna assists Sixth Street in our long-term efforts to identify, evaluate, and advance commercial development opportunities within the CRISPR and gene-editing ecosystem. She is also leading the build of our Scientific Advisory Board, which will advise our team as we continue to finance the development and commercialization of innovative therapeutics and invest in healthcare technology companies across all stages of growth.

Learn More


Select Investments

Alliance Medical

Alliance HealthCare Services

Irvine, CA |

Alliance HealthCare Services is a leading national provider of outsourced medical services including radiology, oncology, and interventional.



New Haven, CT |

Biohaven is a biopharmaceutical company focused on the development and commercialization of best-in-class therapies.

Blueprint Medicines

Blueprint Medicines

Cambridge, MA |

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders.


Caris Life Sciences

Irving, TX |

Caris Life Sciences is a leading innovator in molecular science focused on fulfilling the promise of precision medicine.

Clovis Oncology

Clovis Oncology

Boulder, CO |

Clovis Oncology, Inc. is a biopharmaceutical company focused on acquiring, developing and commercializing innovative anti-cancer agents.



Cambridge, MA |

ConcertAI is a global leader in life sciences and healthcare enterprise AI and RWD SaaS solutions.



San Francisco, CA |

Datavant’s mission is to connect the world’s health data to improve patient outcomes.



Rockville, MD |

DrFirst provides healthcare technology solutions and consulting services that securely connect people at touchpoints of care to improve patient outcomes.

Immunogen Sixth Street


Waltham, MA |

Immunogen is developing the next generation of antibody-drug conjugates (ADCs) aimed at disrupting the progression of cancer and improving outcomes for patients.



Cambridge, MA |

Ironwood Pharmaceuticals is a GI-focused healthcare company focused on creating medicines that make a difference for patients living with GI diseases.

Mammoth Biosciences Sixth Street

Mammoth Biosciences

Brisbane, CA |

Mammoth Biosciences is a biotech company building the next generation of CRISPR products to cure and detect disease.

MD Live Sixth Street


Miramar, FL |

MDLIVE is one of the largest and fastest growing virtual care delivery platforms.

MedeAnalytics Sixth Street


Richardson, TX |

MedeAnalytics is a healthcare analytics innovator enabling healthcare providers and payers across the U.S. and U.K. to make smarter decisions in today’s new healthcare economy.

Medsphere Sixth Street


Carlsbad, CA |

Medsphere Systems Corporation is an organization of committed clinical and technology professionals working to positively impact patient care by delivering healthcare IT solutions.

Nektar Sixth Street


Miramar, FL |

Nektar Therapeutics is a research-based, development stage biopharmaceutical company whose mission is to discover and develop innovative medicines.

Therapeutics MD Sixth Street


Boca Raton, FL |

TherapeuticsMD, Inc. is an innovative, leading healthcare company focused on developing and commercializing novel products exclusively for women.



Santa Rosa, CA |

VisiQuate is a leading provider of advanced analytics and AI-powered automation offerings to healthcare providers.

**Sixth Street assets under management excludes (1) TOP I, which was invested as a series of commitments across multiple vehicles sponsored by our former affiliate and (2) assets and commitments of certain vehicles established by Sixth Street for the purpose of facilitating third party co-invest opportunities. Calculation of assets under management differs from the calculation of regulatory assets under management and may differ from the calculations of other investment managers.